We can never know enough to compete with the person who knows more. In the current information - infonomic - society, knowledge is cheap while expertise is premium. Lack of knowledge is an opportunity to learn something new, be more enlightened and more sensitive, and in this I only see positives, benefits.
Although it can be worrisome to think, ‘I don’t know enough about X’, ‘I wish I had the time to better understand Y,’ it isn’t - or shouldn’t be - a lack of knowledge itself causing the anxiety. What we really mean is, ‘I wish I had the expertise to execute X or Y.’ There are those with more knowledge who will not achieve a quarter of your success, notwithstanding of course that success, in itself, is relative. However, it is expertise that makes you an expert, not knowledge. Knowledge gives you the means to acquire expertise, but it does not guarantee it.